IGF-1 LR3 1 mg (Research Use Only)
Long-Acting Insulin-Like Growth Factor Analog for Research
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long Arg³) is a synthetically modified IGF-1 analog designed for extended biological activity and reduced binding to IGF-binding proteins (IGFBPs). These modifications make IGF-1 LR3 a valuable research tool for studying cell growth, differentiation, and anabolic signaling pathways.
Product Overview
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Product Name: IGF-1 LR3
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Strength: 1 mg per vial
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Purity: ≥ 99 % (HPLC verified)
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Form: Lyophilized powder
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Peptide Type: Recombinant IGF-1 analog
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Molecular Weight: ~9.1 kDa
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Intended Use: Research Use Only (RUO)
Key Features
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Long-acting IGF-1 analog with enhanced stability
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Reduced affinity for IGF-binding proteins
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Prolonged receptor interaction in experimental models
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High purity suitable for advanced laboratory research
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Supplied as sterile, lyophilized powder
Mechanism of Action (Research Context)
In investigational research, IGF-1 LR3 is studied for its ability to:
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Bind to IGF-1 receptors (IGF-1R) with prolonged activity
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Activate PI3K/Akt and MAPK signaling pathways
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Promote cellular proliferation and differentiation in vitro
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Support anabolic signaling in muscle and connective tissue research
The LR3 modification extends peptide persistence compared to native IGF-1, allowing researchers to evaluate sustained growth factor signaling.
Mechanistic descriptions are based on experimental and preclinical research. IGF-1 LR3 is not an approved therapeutic agent.
Technical Specifications
| Parameter | Specification |
|---|---|
| Peptide Content | 1 mg |
| Purity | ≥ 99 % |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or dilute acid |
| Molecular Weight | ~9.1 kDa |
| Storage (Lyophilized) | –20 °C, protect from light |
| Storage (Reconstituted) | 2–8 °C; avoid freeze–thaw cycles |
Reconstitution & Storage
Reconstitution
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Reconstitute with sterile water or appropriate buffer
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Gently swirl until fully dissolved
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Do not shake vigorously
Storage
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Store unopened vials at –20 °C
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Refrigerate reconstituted solutions (2–8 °C)
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Use according to standard peptide-handling protocols
Research Applications
IGF-1 LR3 is commonly used in research focusing on:
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Cell growth and proliferation studies
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Muscle hypertrophy and regeneration research
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Anabolic and metabolic signaling pathways
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IGF-1 receptor and downstream pathway analysis
Quality & Compliance
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Produced via recombinant peptide technology
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Verified by HPLC and mass spectrometry
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Certificate of Analysis (COA) available upon request
Important Notice
⚠ For Research Use Only (RUO)
This product is not approved for human or veterinary use and is not intended for consumption.
Use only in accordance with institutional and regulatory guidelines.
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