MT-2 (Melanotan 2 Acetate)

Important Statement: This product is a high-purity synthetic peptide research reagent, strictly for in vitro research use only (For Research Use Only). It is not suitable for human use, clinical diagnosis, drug purposes, health, beauty, or any other non-research applications. It must be handled by qualified personnel in a professional laboratory environment that complies with all applicable regulations.

1. Product Overview
This product, MT-2 (Melanotan II Acetate), is the acetate salt form of Melanotan II, a cyclic peptide analog prepared by solid-phase peptide synthesis. As a potent, non-selective melanocortin receptor agonist, it serves as a crucial in vitro tool compound for studying the melanocortin system and related signaling pathways. The product is supplied as a white to off-white lyophilized powder, ensuring high stability and reconstitution properties.

2. Key Features

• High Purity: Verified by High-Performance Liquid Chromatography (HPLC) analysis, with a purity of ≥ 98%.

• Defined Structure: Precise molecular weight (C₅₀H₆₉N₁₅O₉·xC₂H₄O₂, to be calculated) and cyclic amino acid sequence are provided to guarantee experimental reproducibility.

• Rigorous Quality Control: Subjected to multiple biological reagent standard tests, including sterility, low endotoxin levels (<1.0 EU/mg), and residual solvent analysis.

• Stable Formulation: The acetate salt form enhances stability. The lyophilized powder facilitates transportation and long-term storage at -20°C in a dry environment.

3. Primary Research Applications (Examples)

• Receptor Pharmacology Studies: Used for the in vitro evaluation of its affinity, selectivity, and agonist activity for various melanocortin receptors (MC1R, MC3R, MC4R, MC5R).

• Cell Signaling Pathway Research: Investigates the molecular mechanisms of its activation of downstream signaling pathways such as cAMP/PKA and MAPK.

• Bioactivity Screening Models: Serves as a positive control or tool compound in developing screening platforms for novel compounds targeting melanocortin receptors.

• Animal Behavior Research (In Vitro Tissue Level): Can be used in ex vivo tissue experiments to study physiological mechanisms potentially related to receptor activation.

4. Usage and Storage

• Reconstitution using sterile saline or a specific buffer (e.g., PBS containing 0.1% BSA) is recommended.

• After reconstitution, it should be aliquoted immediately and stored frozen at -20°C or below to avoid repeated freeze-thaw cycles.

• Note: This product possesses significant bioactivity. Appropriate personal protective equipment (PPE) should be worn, and operations should be conducted under professional ventilation.

5. Disclaimer
This product is sold as a research chemical only. The purchaser and user must be qualified scientific researchers or institutions and must ensure all research activities are legal and compliant. This description does not constitute any medical, cosmetic, or efficacy advice. The manufacturer and seller expressly disclaim any liability for consequences arising from the use of this product in humans, animals, drug formulation, or incorporation into consumer products, and assume no responsibility for any such outcomes.