Thymalin 10mg

Thymalin 10 mg — Technical Product Information

1. Product Overview

Thymalin is a research‑grade peptide preparation comprised of a mixture of low‑molecular‑weight thymic peptides originally characterized from thymus gland extracts. It is primarily used in scientific research investigating immune modulation, cellular differentiation, and peptide‑mediated regulation of biological pathways.

• Product Name: Thymalin

• Formulation: Lyophilized peptide powder

• Nominal Content: 10 mg per vial

• Intended Use: For research purposes only (RUO); not for human or veterinary use.

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2. Physical & Chemical Specifications

Note: Because Thymalin represents a peptide complex rather than a single defined entity, specific molecular weight and sequence data vary by preparation and analytical characterization.

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3. Composition & Peptide Characteristics

Thymalin preparations contain a heterogeneous mixture of thymic peptides, typically enriched for small bioactive sequences derived from calf thymus tissue. These peptides range in length and may include:

• Tri‑ and oligopeptides such as Glu‑Asp‑Pro and Lys‑Glu‑Asp identified in analytical studies.

• A range of short thymic factors historically associated with thymopoietic regulation.

Exact component proportions and peptide identities depend on extraction and purification methods.

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4. Mechanism of Action (Research Context)

Thymalin’s biological activity in research settings is associated with several cellular and molecular effects:

• Immune cell modulation: Influences differentiation and activity of T‑lymphocytes, including expression of T‑cell receptor components and cytokine receptors, supporting research models of immune regulation.

• Cytokine balance: Modulates production of key immune signaling molecules (e.g., IL‑2, IFN‑γ) in experimental systems.

• Hematopoietic influences: Peptide components have been linked to enhanced early progenitor cell differentiation in vitro and ex vivo.

• Gene expression: Short peptides may interact with DNA/histone proteins, affecting transcriptional regulation of immune‑related genes in research models.

These mechanisms are subjects of ongoing scientific investigation and are not established as approved mechanisms for clinical therapeutics.

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5. Reconstitution & Handling Guidelines (Research)

Reconstitution (for laboratory use only):

1. Prepare a sterile work area and wear appropriate PPE.

2. Add sterile water for injection, bacteriostatic water, or 0.9 % saline to the vial (commonly 1–2 mL, depending on assay needs).

3. Gently swirl to dissolve; do not shake vigorously.

4. Label with reconstitution date/time and concentration.

5. Store reconstituted solution at 2–8 °C; use within a limited timeframe per institutional protocol.

Handling:

• Follow institutional biosafety and hazardous material guidelines.

• Avoid introducing contaminants or repeated freeze–thaw cycles.

• Dispose of unused solution per laboratory hazardous waste protocols.

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6. Research Applications

Thymalin is commonly used in scientific research exploring:

• Cellular and molecular immune regulation pathways.

• Experimental models of aging and immunosenescence.

• Studies of thymopoiesis and lymphocyte differentiation.

• Investigations of peptide‑peptide and peptide‑DNA interaction dynamics.

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7. Safety & Regulatory Notes

• For research use only (RUO) — not approved as a pharmaceutical, therapeutic, dietary supplement, or clinical diagnostic.

• Not for human or animal administration.

• Users must adhere to applicable institutional and legal restrictions on peptide handling and experimentation.